Extracellular miRNAs for predicting risk following acute myocardial infarction: a narrative review

Background and Objective: Acute myocardial infarction (AMI) is a leading cause of morbidity mortality worldwide, survivors are at an increased risk experiencing adverse left ventricular (LV) remodelling major cardiovascular events (MACE). As such, the development non-invasive tools to predict following AMI remains clinical priority. MicroRNAs (miRNAs) small-noncoding RNAs that regulate gene expression have come prominence as novel class circulating biomarkers in AMI. In this narrative review, we summarise current evidence links miRNAs with parameters LV MACE AMI, investigate challenges must be overcome facilitate translation into use.